Recent Researches In Dementia

 

<p style="&quot;text-align:" justify;"=""> Research focused on beta-amyloid, however, hasn’t panned out in the way many had hoped. Many of the late-stage drug trials reporting negative results in recent years have been tests of treatments targeting the protein. There’s a silver lining, however: much of the knowledge we have gained about other potential treatments, and how to properly conduct clinical trials in people with and at risk for Alzheimer’s, has been from studies that, by the standard metrics, would be considered failures. Researchers are still trying to understand the role of beta-amyloid in Alzheimer’s disease, but are also exploring new potential treatment targets ranging from brain inflammation to the gut microbiome. It’s found that bone marrow stem cells are effective at fighting inflammation—and there is now research underway into whether they could do the same if introduced into the brain. Our understanding of the role of the gut microbiome in Alzheimer’s is in its infancy, but, thanks to the early research focused on beta-amyloid, we now know that lipids and other digestive chemicals wind up in the brain, which means they might be manipulated microbially as a treatment approach.

 

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